Cacna1a CLIA Kit for Rat(Rattus norvegicus) | EIAab.comCacna1a CLIA Kit for Rat(Rattus norvegicus)

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Cacna1a (Gene name),

Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Protein name ), CAC1A_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacna1a(Cach4;Cacn3;Cacnl1a4);

Protein name:

Voltage-dependent P/Q-type calcium channel subunit alpha-1A;

Alternative:

Calcium channel, L type, alpha-1 polypeptide, isoform 4;Brain calcium channel I(BI);Voltage-gated calcium channel subunit alpha Cav2.1;Rat brain class A(RBA-I);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interact (via C-terminal CDB motif) with CABP1 in the pre- and postsynaptic membranes.

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2212

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PSEGREHATH | RQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF08763

UniGene:

Rn.87769

KEGG:

rno:25398

String:

P54282

Uniprot:

P54282

FOR

ELISA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344r

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96T

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ELISA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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ELISA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344m

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Packing:

96T

CLIA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Monoclonal Antibody for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Protein for Rat Voltage-dependent P/Q-type calcium channel subunit alpha-1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Primary structure of a calcium channel that is highly expressed in the rat cerebellum."
Starr T.V.B. , Prystay W. , Snutch T.P.
Proc. Natl. Acad. Sci. U.S.A.88:5621-5625(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Brain.
2.

"Molecular characterization and nephron distribution of a family of transcripts encoding the pore-forming subunit of Ca2+ channels in the kidney."
Yu A.S.L. , Hebert S.C. , Brenner B.M. , Lytton J.
Proc. Natl. Acad. Sci. U.S.A.89:10494-10498(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1354-1659 (ISOFORM 2)
tissue: Kidney.
3.

"Rat brain expresses a heterogeneous family of calcium channels."
Snutch T.P. , Leonard J.P. , Gilbert M.M. , Lester H.A. , Davidson N.
Proc. Natl. Acad. Sci. U.S.A.87:3391-3395(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1435-1667 (ISOFORM 3)
4.

"Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1."
Lee A. , Westenbroek R.E. , Haeseleer F. , Palczewski K. , Scheuer T. , Catterall W.A.
Nat. Neurosci.5:210-217(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CABP1

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